F.R. DOUWES, M.D.; L. REICHEL, M.D.
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Lauter and associates reported (Ann Intern Med 79:59-62, 1973) a significant stimulation of nitroblue tetrazolium dye (NBT) reduction in patients with acute myocardial infarction, compared with patients suffering from infectious disease. They speculate that this granulocytic stimulation could be caused by fibrin, fibrinogen, and the breakdown products of these proteins. We have not been able to confirm their observation. In our earlier studies we reported that myocardial infarction, even if it is associated with leukocytosis or fever, does not result in a higher rate of NBT reduction. Since the publication of Lauter's findings, we have studied 21 cases of acute
DOUWES F, REICHEL L. NBT Test in Myocardial Infarction. Ann Intern Med. ;80:277–278. doi: 10.7326/0003-4819-80-2-277_2
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Published: Ann Intern Med. 1974;80(2):277-278.
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