DAVID B. SACHAR, M.D., F.A.C.P.; ROBERT S. KLEIN, M.D.; FREDERICK SWERDLOW, M.D.; EDWARD BOTTONE, Ph.D.; MANSHO T. KHILNANI, M.D.; JEROME D. WAYE, M.D., F.A.C.P.; MARIAN WISNIEWSKI, M.D.
A 42-year-old man with positive blood and spinal fluid findings for syphilis had clinical, radiologic, gastroscopic, and histologic evidence of a severe infiltrative and erosive gastritis involving the entire distal stomach. Gastric tissue obtained from gastroscopic biopsy contained numerous motile spirochetes on dark-field microscopy, with strongly positive specific treponemal immunofluorescence. The abnormalities resolved after a course of penicillin therapy. This case shows the propensity of late secondary syphilis to produce mucosal lesions in the stomach.
SACHAR DB, KLEIN RS, SWERDLOW F, et al. Erosive Syphilitic Gastritis: Dark-Field and Immunofluorescent Diagnosis from Biopsy Specimen. Ann Intern Med. 1974;80:512–515. doi: 10.7326/0003-4819-80-4-512
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Published: Ann Intern Med. 1974;80(4):512-515.
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