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Attempts to develop better chemical contraceptives for intravaginal use have a long history; the ancient Egyptians thus used the acacia plant to prevent pregnancy. Acacia contains a gum that forms lactic acid, a common ingredient of many spermicides today. Such historical notes are not uncommon in Dr. Bennett's brief but thorough history of the development of chemical contraceptives from the late 19th century to the present (the latest references are to the literature of 1971). This history proceeds from the use of mechanical barriers between the ovum and sperm, with or without spermicides, to the so-called first generation of hormonal
Chemical Contraception.. Ann Intern Med. ;81:422–423. doi: 10.7326/0003-4819-81-3-422_2
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Published: Ann Intern Med. 1974;81(3):422-423.
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