RICHARD J. MANGI, M.D.; JOHN M. DWYER, M.D., PH.D.; JAMES C. NIEDERMAN, M.D.; FRED S. KANTOR, M.D.
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To the editor: During the course of investigation of delayed hypersensitivity in cases of acute infectious mononucleosis, we have recently seen reversal of the normal peripheral blood T:B cell ratio in a controlled study of seven patients (Table 1) with presumed viral infections of the upper respiratory tract. These patients had pharyngitis, cervical adenopathy, and nonproductive cough
for less than 1 week. One patient (Patient 1) did develop pulmonary congestion and sputum production. Heterophil antibody was not present, and culture of the pharynx for B-hemolytic streptococci was negative in all patients. T cells were detected by formation of rosettes with
MANGI RJ, DWYER JM, NIEDERMAN JC, et al. Decreased Circulating T Cells During Viral Pharyngitis. Ann Intern Med. 1974;81:557–558. doi: 10.7326/0003-4819-81-4-557_2
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Published: Ann Intern Med. 1974;81(4):557-558.
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