BARRY KISLOFF, M.D.
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To the editor: In the review, "The Pathogenesis of Hypercholesterolemia" (Ann Intern Med 80:738-746, 1974), the author states that alcohol has little effect on the blood cholesterol level.
It has been repeatedly shown in humans (1-3), dogs (1), and rats (4, 5) that when ethanol is given in quantities sufficient to make up at least 24% of the total caloric intake or when given in substantial quantity (approximately 90 g or 9 oz per day) there will be a significant increase in both hepatic content and serum concentration of cholesterol.
The references quoted by the author (1, 6) in support
KISLOFF B. Alcohol and Cholesterol. Ann Intern Med. ;81:712. doi: 10.7326/0003-4819-81-5-712_1
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Published: Ann Intern Med. 1974;81(5):712.
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