KIRON M. DAS, M.D., PH.D.; WILLIAM F. ERBER, M.D.
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To the editor: We read with interest the article on clindamycin-associated colitis by Tedesco, Barton, and Alpers (1) and the editorial (2) published in the October issue of the Annals. We wish to report a case of clindamycin-associated colitis, in which we studied the electron microscopic and immunohistochemical features of the colonic mucosa in addition to other routine examinations.
This 79-year-old white man developed the syndrome with profuse watery diarrhea without blood after a 2-week course of clindamycin therapy. Barium enema showed the features consistent with ulcerative colitis. Colonoscopy showed classical yellowish white plaques (1 to 6 mm in diameter)
DAS KM, ERBER WF. Clindamycin-Associated Colitis. Ann Intern Med. ;82:426–427. doi: 10.7326/0003-4819-82-3-426_2
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Published: Ann Intern Med. 1975;82(3):426-427.
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