HARRIS A. LAPPIN, M.D.
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To the editor: Dowling and associates (1) have described in your journal a case of bacterial endocarditis caused by Neisseria mucosa in a patient with Marian's syndrome. Endocarditis is a well-described complication of the mitral valve prolapse-click syndrome (MVP-CS), as reviewed by Jeresaty (2). There is also strong support for the concept that MVP-CS is a forme fruste of Marfan's disease (3). It would therefore not be surprising to discover on rare occasion a patient with Marfan's syndrome and endocarditis from almost any organism.
The case report implies that the endocarditis in this patient occurred in the presence of penicillin
LAPPIN HA. Endocarditis in Marian's Syndrome. Ann Intern Med. 1975;82:432–433. doi: https://doi.org/10.7326/0003-4819-82-3-432
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Published: Ann Intern Med. 1975;82(3):432-433.
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