ROBERT MATZ, M.D., F.A.C.P.
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To the editor: It is unfortunate that "concepts" remain entrenched in medicine while facts are ignored until they overwhelm the concept. I refer to the editorial note by Molnar and Service (1) in the December 1974 issue.
In 1962 Shaw and associates (2) showed that low doses of insulin were just as effective as high doses in correcting diabetic ketoacidosis. In 1954 Smith and Martin (3) reported that the time required to lower the blood sugar to 300 mg/100 ml and to raise the serum bicarbonate to 20 meq/litre was not influenced by changes in insulin dosage from 80 to
MATZ R. "Concepts" in Diabetes Mellitus. Ann Intern Med. ;82:853. doi: 10.7326/0003-4819-82-6-853_1
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Published: Ann Intern Med. 1975;82(6):853.
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