GERARDO AYALA, M.D.; BRUCE S. CHERTOW, M.D., F.A.C.P.; JAYENDRA H. SHAH, M.D.; GERALD A. WILLIAMS, M.D., F.A.C.P.; SUBHASH C. KUKREJA, M.D.
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Intravenous phosphate therapy alone or combined with oral phosphate therapy on occasion has caused metastatic calcification and renal impairment (1). This report documents a case in which oral phosphate therapy alone was associated with acute hyperphosphatemia and acute onset of persistent renal insufficiency.
A 64-year-old black man with primary hyperparathyroidism was hospitalized for a neck exploration. Because of symptoms and signs of congestive heart failure and an electrocardiogram that showed changes consistent with a recent myocardial infarction, surgery was postponed.
Admission laboratory data included the following: hematocrit, 36.2%; leukocyte count, 5200/mm3; blood urea nitrogen, 16 mg/100 ml (normal, 10 to
AYALA G, CHERTOW BS, SHAH JH, WILLIAMS GA, KUKREJA SC. Acute Hyperphosphatemia and Acute Persistent Renal Insufficiency Induced by Oral Phosphate Therapy. Ann Intern Med. ;83:520–521. doi: 10.7326/0003-4819-83-4-520
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Published: Ann Intern Med. 1975;83(4):520-521.
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