JEFFREY T. KESSLER, M.D.
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To the editor: The study of Hunder and colleagues (Ann Intern Med 82:613-618, 1975) showed daily administration of corticosteroids to be superior to an alternate-day regimen in the initial management of giant cell arteritis. However, it may be premature to totally discard the concept of alternate-day steroid therapy in this disease, for two reasons.
First, some patients in the alternate-day nonresponder group apparently derived significant benefit on the days that they received steroids, since "typically, the patients receiving alternate-day therapy who did not respond completely felt reasonably well during some portion of the day on which 90 mg of prednisone
KESSLER JT. Alternate-Day Steroid Therapy. Ann Intern Med. 1975;83:734. doi: https://doi.org/10.7326/0003-4819-83-5-734_1
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Published: Ann Intern Med. 1975;83(5):734.
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