JERRY L. YON, M.D.; SINN ANURAS, M.D., F.A.C.P.; KENNETH WU, M.D., F.A.C.P.; E. LEE FORKER, M.D.
Two young patients presented with an unusual liver disease, granulomatous hepatitis with postnecrotic cirrhosis, and both underwent a splenorenal shunt procedure. Each developed an arterial embolic episode probably related to increased platelet aggregation. This represents the first report of a liver disease associated with increased platelet aggregation that was clinically significant, a myocardial infarction in one and a posterior cerebral infarction in the other. Also, unexpectedly, both patients became hypercholesterolemic after the splenorenal shunt was established.
YON JL, ANURAS S, WU K, et al. Granulomatous Hepatitis, Increased Platelet Aggregation, and Hypercholesterolemia. Ann Intern Med. 1976;84:148–150. doi: 10.7326/0003-4819-84-2-148
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Published: Ann Intern Med. 1976;84(2):148-150.
Cardiology, Coronary Risk Factors, Dyslipidemia, Gastroenterology/Hepatology, Liver Disease.
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