PETER E. DANS, M.D., F.A.C.P.
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To the editor: Doctor Jaffe, in his timely and excellent review entitled "The Laboratory Diagnosis of Syphilis" (Ann Intern Med 83:846-850, 1975), states that "the combination of a clinically suspicious lesion and a reactive RPR card test is sufficient to initiate therapy during the first visit." The judgment "clinically suspicious" is determined by the experience of the observer as much as by the lesion. Many physicians graduating from medical school in the last 2 decades have never seen a chancre and have little basis for designating a lesion as "typical" or "clinically suspicious." To further complicate matters, physicians are taught
DANS PE. Venereal Disease: Diagnosis and Treatment. Ann Intern Med. ;84:491. doi: 10.7326/0003-4819-84-4-499_1
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Published: Ann Intern Med. 1976;84(4):491.
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