J. DONALD COONROD, M.D., F.A.C.P.; RICHARD P. LEACH, M.D.
Two asplenic patients with fulminant pneumococcemia developed purpura and coagulopathy. Levels of C3 and C4 in the serum were low. Both patients had high levels of circulating capsular polysaccharide, and one patient had visible diplococci on a smear of the peripheral blood. Pneumococcal group C polysaccharide (C-substance) was detected in the serum of one of the patients. Possible pathogenetic relation of circulating pneumococcal antigens to the development of coagulopathy in pneumococcemia is discussed.
COONROD JD, LEACH RP. Antigenemia in Fulminant Pneumococcemia. Ann Intern Med. 1976;84:561–563. doi: 10.7326/0003-4819-84-5-561
Download citation file:
Published: Ann Intern Med. 1976;84(5):561-563.
Coagulopathies, Hematology/Oncology, Hospital Medicine.
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use