LAURENCE E. STEMPEL, M.D.
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To the editor: In the May issue, Spark and associates (Ann Intern Med 84:532-537, 1976) described the successful treatment of the galactorrhea-amenorrhea syndrome with bromergocryptine. Fifteen women, including four with pituitary tumors, received the drug; galactorrhea remitted in all, and ovulatory menses resumed in 14 of the 15. Four women, two with pituitary tumors, became pregnant while taking the drug.
This article is disturbing for several reasons. First, the teratogenicity of bromergocryptine has not been adequately studied. Although preliminary reports indicate that it is not teratogenic in rats or rabbits (1), relatively few women have thus far become pregnant while
STEMPEL LE. Bromergocryptine and the Galactorrhea-Amenorrhea Syndrome. Ann Intern Med. 1976;85:401–403. doi: https://doi.org/10.7326/0003-4819-85-3-401
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Published: Ann Intern Med. 1976;85(3):401-403.
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