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To the editor: In reference to the excellent work reported by Jordan and associates (1) I would like to make several points. The elevation of cerebrospinal fluid (CSF) prolactin should more properly be looked on as a nonspecific response to alterations in the serum hormone concentration rather than a manifestation of extrasellar growth of a pituitary tumor.
This is substantiated by the increased CSF prolactin reported in association with conditions of non-neoplastic hyperprolactinemia either naturally occuring—during pregnancy or neonatal life (2), proestrous in rats (3), or iatrogenic—after intravenous prolactin injection into rabbits (3), or in treatment of patients with psychoactive
LOGIN IS. Spinal Fluid Prolactin. Ann Intern Med. 1977;86:119–120. doi: https://doi.org/10.7326/0003-4819-86-1-119
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Published: Ann Intern Med. 1977;86(1):119-120.
DOI: 10.7326/0003-4819-86-1-119
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