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Prohormones, their conversion into active forms, heterogeneity of circulating peptide hormones, and hormone-receptors interactions are reviewed in this symposium. The heterogeneity of polypeptide hormones seems to play a physiologic role in regulation of potency and duration of action. The interconversion of hormone forms controls the effect. Specific polypeptide hormones discussed include insulin, glucagon, β-MSH, ACTH, growth hormone, parathyroid hormone, gastrin and somatostatin.
Polypeptide Hormones: Molecular and Cellular Aspects.. Ann Intern Med. ;86:377. doi: 10.7326/0003-4819-86-3-377_9
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Published: Ann Intern Med. 1977;86(3):377.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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