CARL R. KJELDSBERG, M.D.
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To the editor: Yam, Chaudry, and Janckila (1) have recently described impaired leukocyte mobilization in leukemic reticuloendotheliosis (hairy cell leukemia). Using the skin window technique of Rebuck and Crowley (2), they showed lack of monocyte response. The authors postulate that factors other than monocytopenia could explain the lack of monocyte response and suggest an intrinsic monocyte defect or a lack of chemotactic factors.
We wish to report briefly on a study that may explain some of their findings. Sera from five patients with leukemic reticuloendotheliosis were examined for the presence of chemotactic factor inactivator(s). A suspension of bacterial chemotactic factor
KJELDSBERG CR. Leukocyte Mobilization in Leukemic Reticuloendotheliosis. Ann Intern Med. 1978;88:268–269. doi: 10.7326/0003-4819-88-2-268_2
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Published: Ann Intern Med. 1978;88(2):268-269.
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