A. FONTANA, M.D.; P. J. GROB, M.D.
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To the editor: In the January 1977 issue Van Thiel and associates (1) reported on "A Syndrome of Immunoglobulin A Deficiency, Diabetes Mellitus, Malabsorption, and a Common HLA Haplotype." We wish to emphasize further a remarkable feature present in two of the three reported cases: Patient 12 was "on at least two occasions . . . hospitalized for a seizure disorder that may have been related to difficulties in managing her diabetes in the presence of malabsorption"; and Patient 17 had so-called idiopathic epilepsy.
We have recently reported on the association of IgA deficiency with epilepsy. Measurement of the IgA
FONTANA A, GROB PJ. Immunoglobulin Deficiency, HLA Antigens, and Seizures. Ann Intern Med. 1978;88:429. doi: https://doi.org/10.7326/0003-4819-88-3-429_2
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Published: Ann Intern Med. 1978;88(3):429.
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