RANDALL A. AMMON, M.D.; W. STRATFORD MAY, M.D.; STEPHEN D. NIGHTINGALE, M.D.
A diabetic patient exhibited glucose-induced hyperkalemia despite normal plasma and urinary aldosterone levels. The patient received no diuretics, was not acidotic, and had a creatinine clearance of 39 ml/min. Insulin or pharmacologic doses of desoxycorticosterone acetate eliminated the glucose-induced hyperkalemia. Normal aldosterone levels may be insufficient to protect certain diabetic patients from glucose-induced hyperkalemia.
AMMON RA, MAY WS, NIGHTINGALE SD. Glucose-Induced Hyperkalemia with Normal Aldosterone Levels: Studies in a Patient with Diabetes Mellitus. Ann Intern Med. 1978;89:349–351. doi: 10.7326/0003-4819-89-3-349
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Published: Ann Intern Med. 1978;89(3):349-351.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism, Fluid and Electrolyte Disorders.
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