STANLEY C. DERESINSKI, M.D.
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To the editor: The concise review of malignant pleural effusion by Leff, Hopewell, and Costello (1) was a delight to read. I would, however, like to comment on their statement that "eosinophils are absent" from such effusions.
The reference given by the authors for this assertion states only that "increased numbers of eosinophils in an effusion suggest infection or infarction" (2). The presence of eosinophils in pleural effusions appears to be a relatively nonspecific finding and by no means eliminates malignant disease as a cause. In three published series, infection was the cause in 10% to 24% of cases while
DERESINSKI SC. Eosinophils, Pleural Effusions, and Malignancy. Ann Intern Med. 1978;89:424–425. doi: https://doi.org/10.7326/0003-4819-89-3-424_2
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Published: Ann Intern Med. 1978;89(3):424-425.
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