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Letters |1 September 1978

Vitamin B12 Analogues and Bacterial Overgrowth

HENRY FOY; ATHENA KONDI

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Author, Article, and Disclosure Information
  • Wellcome Trust Research Laboratories and National Public Health Laboratory Service
    P.O. Box 43640; Nairobi
    ,
    Kenya
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Abstract

To the editor: Your November 1977 issue has just arrived, and we have read the article by Brandt, Bernstein, and Wagle (1), "Production of Vitamin B12 Analogues in Patients with Small-Bowel Bacterial Overgrowth."

Some years ago we reported (2, 3) the response to 200 000 to 400 000 IU of oral or intramuscular penicillin daily for 6 to 12 days in Africans with gross nonpernicious megaloblastic anaemias and haemoglobin counts as low as 2g/100 ml. These patients also responded to 80 µg of oral or intramuscular vitamin B12. On entrance the patients had low serum B12 levels (20 to 100

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FOY H, KONDI A. Vitamin B12 Analogues and Bacterial Overgrowth. Ann Intern Med. 1978;89:430. doi: 10.7326/0003-4819-89-3-430_1

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Published: Ann Intern Med. 1978;89(3):430.

DOI: 10.7326/0003-4819-89-3-430_1

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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