ALLAN P. FREEDMAN, M.D.; JAMES P. SHINNICK, D.O.; PAUL B. SOLNICK, M.D.
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To the editor: We were pleased to note the report from the National Naval Medical Center relating their experience with acetylcysteine instillation in cases of bronchial mucous plugging (Ann Intern Med 88:656, 1978). For several years we have been instilling 5-ml aliquots of 10% acetylcysteine through the fiber-optic bronchoscope in cases of atelectasis due to thick retained secretions when aggressive chest physiotherapy did not result in significant resolution. In these cases, we have found the subsequent liquefaction of thick mucoid secretions quite helpful. We believe that some of these cases would have required rigid endoscopy had acetylcysteine not been used.
FREEDMAN AP, SHINNICK JP, SOLNICK PB. Acetylcysteine for Bronchial Plugging. Ann Intern Med. 1978;89:431. doi: https://doi.org/10.7326/0003-4819-89-3-431_2
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Published: Ann Intern Med. 1978;89(3):431.
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