LOUIS Y. KORMAN, M.D.; J. ROBERT SMITH, M.D.; STEPHEN A. LANDAW, M.D., Ph.D.; FREDERICK R. DAVEY, M.D.
This content is PDF only. Please click on the PDF icon to access.
Bone marrow failure as a result of marrow involvement has been considered the major cause of pancytopenia in patients with Hodgkin's disease. We describe here the case of a patient with lymphocyte-depletion Hodgkin's disease in which the destruction of blood elements by intramedullary macrophages resulted in severe, refractory pancytopenia.
A 62-year-old white man presented with a 2-month history of night sweats and weight loss. At physical examination he was icteric; his temperature was 38 °C, pulse 90/min, respiratory rate 16/min, and blood pressure 90/60 mm Hg. Liver span measured 13 to 14 cm; the spleen tip was palpable. Ascites and
KORMAN LY, SMITH JR, LANDAW SA, et al. Hodgkin's Disease: Intramedullary Phagocytosis with Pancytopenia. Ann Intern Med. 1979;91:60–61. doi: 10.7326/0003-4819-91-1-60
Download citation file:
Published: Ann Intern Med. 1979;91(1):60-61.
Results provided by:
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use