NANCY GUTENSOHN, S.M.; PHILIP COLE, M.D., DR. P.H.
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To the editor: In a recent report on immunity in Hodgkin's disease in the October 1978 issue, Vianna and Polan (1) interpret their data as evidence that rates of Hodgkin's disease in childhood increases as sibship size increases. This is based on their comparison of the sibship size distribution of 90 children with Hodgkin's disease with an expected distribution of sibship sizes. However, their selection of the expected distribution of sibship sizes is incorrect, and, when corrected, their data show no association of risk with family size.
In their Table 2, Vianna and Polan compare the family size distribution of
GUTENSOHN N, COLE P. Immunity in Hodgkin's Disease. Ann Intern Med. 1979;91:316–317. doi: 10.7326/0003-4819-91-2-316
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Published: Ann Intern Med. 1979;91(2):316-317.
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