JAMES W. MOSLEY, M.D.
This content is PDF only. Please click on the PDF icon to access.
The discovery at the end of the 1960s that the Australia antigen (now called hepatitis B surface antigen [HBsAg]) is a component of hepatitis B virus (HBV) opened the door to preparation of hepatitis B immune globulin (HBIG) having titers of specific antibody (anti-HBs) many hundredfold times higher than those in standard immune serum globulin (ISG). As rapidly as anti-HBs-rich units of plasma could be identified and batches of HBIG prepared, studies of prophylaxis of type B hepatitis were carried out (1-6). Unfortunately, these investigations did not provide an easily interpretable answer to relative usefulness of HBIG and ISG. Hence,
MOSLEY JW. Hepatitis B Immune Globulin: Some Progress and Some Problems. Ann Intern Med. 1979;91:914–916. doi: 10.7326/0003-4819-91-6-914
Download citation file:
Published: Ann Intern Med. 1979;91(6):914-916.
Results provided by:
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use