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Solutions to clinical problems often follow serendipitous insights—for example, the Nobel Prize-winning work of Baruch Blumberg which started in some esoterica of medical anthropology and ended in major advances in our knowledge of hepatitis. E.R. Giblett's serendipitous finding of adenosine deaminase deficiency in patients with severe combined immunodeficiency has opened a new window in clinical immunology. The 20 papers and general discussions in this symposium held in London in November 1978 give authoritative surveys of developments in this field. Recommended for those with clinical investigational interests in infectious disease, clinical immunology, genetic disease, and purine metabolism.
Enzyme Defects and Immune Dysfunction.. Ann Intern Med. ;92:147. doi: 10.7326/0003-4819-92-1-147_1
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Published: Ann Intern Med. 1980;92(1):147.
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