REBECCA S. MASON; DIANNE LISSNER; SOLOMON POSEN, M.D.
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To the editor: Eisman and colleagues (1) have published data concerning the effect of infused parathyroid extract on serum 1,25-dihydroxyvitamin D (1,25diOHD) concentrations in nine normal subjects. We recently had the opportunity to study the effect of an infusion of bovine parathyroid hormone on serum 1,25diOHD levels (2) in two hypoparathyroid patients. The results obtained are presented in Figure 1.
In the patient with surgical hypoparathyroidism (3), there was a clear rise in serum 1,25diOHD with a peak at 14 h. The pseudohypoparathyroid patient, whose baseline serum immunoreactive parathyroid hormone values (4) were elevated, showed no phosphaturic or urinary cyclic
MASON RS, LISSNER D, POSEN S. Parathyroid Hormone Effect on 1,25-Dihydroxyvitamin D in Hypoparathyroidism. Ann Intern Med. ;92:260. doi: 10.7326/0003-4819-92-2-260_1
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Published: Ann Intern Med. 1980;92(2_Part_1):260.
Endocrine and Metabolism, Parathyroid Disorders.
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