NADIR R. FARID, M.B.B.S.
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To the editor: The interesting article by Eisenbarth and colleagues (1) on the polyglandular failure syndrome raises a number of issues that bear discussion. First, because this clinical entity is rare, a variable degree of bias in the selection of a series of patients for study is unavailable. If large series of patients suffering from one autoimmune endocrine disease are examined, as we and Bottazzo (2) have done, for the concurrence of other disorders, a tendency towards ascertainment of a high proportion of patients suffering from insulin-dependent diabetes mellitus is seen. This may be due to selection bias or may
FARID NR. Polyglandular Failure Syndrome. Ann Intern Med. ;92:442–443. doi: 10.7326/0003-4819-92-3-442_2
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Published: Ann Intern Med. 1980;92(3):442-443.
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