M. BRUGUERA, M.D.; F. CERVANTES, M.D.
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To the editor: The statement of Young (1) in the September 1979 issue, that hepatic granulomas are present in infections due to Brucella abortus and absent in those caused by B. melitensis, is not accurate.
Hepatic granulomas have been found in many patients with brucellosis living in Spain, where most cases are due to B. melitensis (2-4). In a recent review of 40 patients with serologically confirmed brucellosis in whom liver biopsy showed a variable degree of hepatic disease, granulomas were found in 28 (70%) (CERVANTES F, BRUGUERA M, CARBONELL J, FORCE L, WEBB S. Liver disease in brucellosis: clinical
BRUGUERA M, CERVANTES F. Hepatic Granulomas in Brucellosis. Ann Intern Med. ;92:571–572. doi: 10.7326/0003-4819-92-4-571_3
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Published: Ann Intern Med. 1980;92(4):571-572.
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