SUMAN WASON, M.D.; ALLAN S. DETSKY, M.D. Ph.D.; ORAH S. PLATT, M.D.; FREDERICK H. LOVEJOY Jr., M.D.
Since 1969, butyl and isobutyl nitrite have been commercially available in products sold as liquid incense and room odorizers. Volatile nitrites are increasingly abused as stimulants, aphrodisiacs, and psychedelic agents, and the manufacturers of one brand of isobutyl nitrite, RUSH (Pacific Western Distributing Corporation; San Francisco, California), have reported over 12 million sales since 1973 (1). These compounds contain greater than 90% nitrites, with small quantities of the corresponding alcohol and vegetable oil to render them less volatile.
A recent monograph on isobutyl nitrite stated that methemoglobinemia, occurring as a result of butyl, isobutyl, and amyl nitrite inhalation, is "clinically
WASON S, DETSKY AS, PLATT OS, LOVEJOY FH. Isobutyl Nitrite Toxicity by Ingestion. Ann Intern Med. 1980;92:637–638. doi: 10.7326/0003-4819-92-5-637
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Published: Ann Intern Med. 1980;92(5):637-638.
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