H. MITCHELL PERRY JR., M.D.
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The article by Mitchell and her colleagues in this issue (1) carries an important practical message: Severely compromised renal function associated with malignant hypertension can be improved by controlling the blood pressure with minoxidil. The report cites three patients, in a series of nine with malignant stages of hypertension, whose creatinine levels of 9 to 13 mg/dL before minoxidil treatment decreased by more than two thirds to 2 to 4 mg/dL during minoxidil treatment. (Note that the authors list four "improved patients," but in one the preminoxidil creatinine level was not very high and the decrease in serum creatinine was
PERRY HM. Minoxidil and Improvement of Renal Function in Uremic Malignant Hypertension. Ann Intern Med. ;93:769–771. doi: 10.7326/0003-4819-93-5-769
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Published: Ann Intern Med. 1980;93(5):769-771.
Cardiology, Coronary Risk Factors, HIV, Hypertension, Infectious Disease.
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