ALBERT S. LEVEILLE, M.D.; FRANK W. NEWELL, M.D.
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To the editor: We read with interest the paper "Mitral Valve Prolapse and Ophthalmoplegia: A Progressive, Cardioneurologic Syndrome" by Darsee and associates (1). We wish to comment on several points.
Some of the confusion regarding patients with external ophthalmoplegia, heart block, and other abnormalities arises because of the overused, obfuscating term "ophthalmoplegia plus" that links clinically similar conditions obviously not related. Patients with external ophthalmoplegia, retinal pigmentary degeneration, heart block, and other abnormalities, who do not have Bassen-Kornzweig or Refsum diseases, have the Kearns-Sayre syndrome. Cases with only one or two findings, but not the complete triad, should be referred
LEVEILLE AS, NEWELL FW. Ophthalmoplegia Syndromes. Ann Intern Med. ;93:931. doi: 10.7326/0003-4819-93-6-931_1
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Published: Ann Intern Med. 1980;93(6):931.
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