MARY LEE, PHARM.D.; ROWEENA N. SCHWARTZ; ROOHOLLAH SHARIFI, M.D.
This content is PDF only. Please click on the PDF icon to access.
To the editor: Recently, cases of warfarin resistance due to unrecognized vitamin K supplementation in liquid nutrition products have been described (1, 2). These reports came coincidentally, as we were managing a patient with apparent anticoagulant resistance due to the same cause. She was a 70-year-old woman who had had pelvic exenteration for carcinoma of the proximal urethra. Over the next 3 weeks she received 3 L of crystalline amino acid solution without vitamin K supplementation, and a 14-day course of chloramphenicol for treatment of Bacteroides fragilis septicemia. During her convalescence she developed an acute episode of deep venous thrombosis
LEE M, SCHWARTZ RN, SHARIFI R. Warfarin Resistance and Vitamin K. Ann Intern Med. ;94:140–141. doi: 10.7326/0003-4819-94-1-140_3
Download citation file:
Published: Ann Intern Med. 1981;94(1):140-141.
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use