LEONARD J. DEFTOS, M.D.; BRIAN P. FIRST, M.D.
Calcitonin is a peptide hormone produced by the C-cells of the thyroid gland. Its main biological effect is to inhibit the resorption of bone. This effect, in combination with a calciuric action of calcitonin, can produce a lowering of blood calcium. These biological effects of calcitonin have made it useful in the treatment of hypercalcemic and hyperresorptive disorders.
DEFTOS LJ, FIRST BP. Drugs Five Years Later: Calcitonin as a Drug. Ann Intern Med. 1981;95:192–197. doi: 10.7326/0003-4819-95-2-192
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Published: Ann Intern Med. 1981;95(2):192-197.
Endocrine and Metabolism, Thyroid Disorders.
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