MASSIMO GALLI, M.D.; FULVIO INVERNIZZI, M.D.
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To the editor: Dr. Levo (1) refers in his comment on the paper by Popp and colleagues (2) to our data (3) in support of the hypothesis of a significant correlation between hepatitis B virus (HBV) infection and essential mixed cryoglobulinemia. Our data, now drawn from 40 cases of essential mixed cryoglobulinemia (27 females and 13 males, mean age 52, 37 ± 12.07) indicate an exposure to HBV in 60% of these cases. We could not, however, find a statistically significant difference between these patients and the control group composed of patients, age and sex matched, hospitalized for noninfectious, neoplastic,
GALLI M, INVERNIZZI F. Hepatitis B Virus and Cryoglobulinemia. Ann Intern Med. 1981;95:522. doi: 10.7326/0003-4819-95-4-522_1
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Published: Ann Intern Med. 1981;95(4):522.
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