SUDHAKER D. RAO, M.B., B.S.; M. KLEEREKOPER, M.B., B.S.; K. TOLIA, M.B., B.S.; V. MATKOVIC, M.D., PH.D.; B. FRAME, M.D.; A.M. PARFITT, M.B., B. CHIR.
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To the editor: Primary hyperparathyroidism is commonly discovered accidentally during routine biochemical screening, and has a prevalence in the general population of 0. 1 to 0.3% (1, 2). By contrast, hypoparathyroidism commonly presents with symptomatic hypocalcemia and its prevalence is not known (3). Six cases of hypoparathyroidism were found accidentally during routine screening.
During an 18-month period (January 1977 to July 1978), 108 000 automated biochemical profiles (SMAC) were done at this institution and six adults were referred for evaluation of unexpected hypocalcemia. Plasma calcium, phosphorus, and total protein were measured by standard methods in the clinical chemistry laboratory. Plasma
RAO SD, KLEEREKOPER M, TOLIA K, et al. Hypothyroidism and Biochemical Screening. Ann Intern Med. 1981;95:655. doi: 10.7326/0003-4819-95-5-655_1
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Published: Ann Intern Med. 1981;95(5):655.
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