BARRY A. WARNER, D.O.; RICHARD J. SANTEN, M.D.; ROBERT B. PAGE, M.D.
Embryologic remnants of tissue with the potential of pituitary function are seen in the pharyngeal region at autopsy as a consistently normal finding in humans (1). Extrapituitary cells can produce syndromes of endocrine hypersecretion, as documented by five reports of tumors arising from embryonic remnants in the sphenoid sinus (2-6). Two of those caused the clinical syndrome of acromegaly (5, 6). However, four of five of these cases antedated development of sensitive hormone assays. We describe the case of a patient with acromegaly who had a mixed growth hormone and prolactin-secreting tumor arising within the sphenoid sinus. Endocrine testing showed
WARNER BA, SANTEN RJ, PAGE RB. Growth Hormone and Prolactin Secretion by a Tumor of the Pharyngeal Pituitary. Ann Intern Med. ;96:65–66. doi: 10.7326/0003-4819-96-1-65
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Published: Ann Intern Med. 1982;96(1):65-66.
Endocrine and Metabolism, Hematology/Oncology, Neurology, Pituitary Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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