A. MARTIN LERNER, M.D.
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The report in this issue by Wade and colleagues (1), from the University of Washington and the Fred Hutchinson Cancer Research Center in Seattle, and the Burroughs Wellcome Co. , describes patients who developed mucocutaneous herpes simplex virus infections after bone marrow transplantation and were successfully treated with acyclovir (acycloguanosine; 9-(2-hydroxyethoxymethyl) guanine; zovirax, acyclovir). A second paper, by Strauss and colleagues (2), from the National Institute of Allergy and Infectious Diseases in Bethesda and the Burroughs Wellcome Co., records a similar accomplishment along with proplylaxis of recurrent mucocutaneous herpes simplex virus infections in five severely immunocompromised patients with nucleoside phosphroylase
LERNER AM. Acyclovir Reaches Clinical Trial. Ann Intern Med. 1982;96:370–372. doi: 10.7326/0003-4819-96-3-370
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Published: Ann Intern Med. 1982;96(3):370-372.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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