ROBERT T. FAILLACE, M.D.; WILLIAM J. KINGSTON, M.D.; NAVIN C. NANDA, M.D.; ROBERT C. GRIGGS, M.D.
Cardiac disease occurs in many forms of neuromuscular diseases (1). We report the occurrence of idiopathic congestive cardiomyopathy associated with amyotrophic chorea and acanthocytosis. Three neurologic disorders are associated with acanthocytosis: the Bassen-Kornzweig syndrome (abetalipoproteinemia); a syndrome characterized by symptoms and signs of a progressive demyelinating disorder of the central nervous system and hypobetalipoproteinemia; and a syndrome of amyotrophic chorea and normobetalipoproteinemia (2-4). Amyotrophic chorea with acanthocytosis is a hereditary neuromuscular syndrome consisting of choreiform movements, limb wasting, and areflexia associated with normolipoproteinemic acanthocytes. However, no person affected with this syndrome has been reported to have coexistent cardiac disease (2-4).
FAILLACE RT, KINGSTON WJ, NANDA NC, GRIGGS RC. Cardiomyopathy Associated with the Syndrome of Amyotrophic Chorea and Acanthocytosis. Ann Intern Med. ;96:616–617. doi: 10.7326/0003-4819-96-5-616
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Published: Ann Intern Med. 1982;96(5):616-617.
Cardiology, Hematology/Oncology, Neurology, Red Cell Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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