JUAN JOSÉ LAHUERTA-PALACIOS; SANTIAGO LARREGLA-GARRAUS; FRANCISCO FERNÁNDEZ-DEBORA; RICARDO RUIZ DE ADANA
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To the editor: Barton and Conrad reported in the February 1979 issue (1) an association of elevation of the aspartate transaminase (AST) levels with improved prognosis of acute myelogenous leukemia. Further data confirming this observation are scarce (2-4), although 2 years have elapsed since it was described.
We wish to point out a critical defect in the studies that have been carried out: The AST level is considered to be the only factor that influences the prognosis. At the time of diagnosis and during the "induction phase" of acute myelogenous leukemia, there are additional simultaneous prognostic factors: classification, previous or
LAHUERTA-PALACIOS JJ, LARREGLA-GARRAUS S, FERNÁNDEZ-DEBORA F, et al. Prognosis of Acute Myelogenous Leukemia. Ann Intern Med. 1982;97:140. doi: https://doi.org/10.7326/0003-4819-97-1-140_1
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Published: Ann Intern Med. 1982;97(1):140.
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