STEVEN L. BERK, M.D.
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To the editor: Drs.Rahal and Simberkoff (1) are to be commended for their detailed and objective discussion of antimicrobial therapy in adult gram-negative bacillary meningitis, a topic that has prompted unusually bitter debate among infectious disease specialists. Such debate about therapy is not unexpected for a disease that is relatively rare, involves a number of different bacterial species with variable antibiotic resistance patterns, has a different clinical presentation depending on the patient, and for which no controlled trials have ever been done. The debate, however, has been fueled by reports of dramatic success against gram-negative bacillary meningitis with third-generation cephalosporins
BERK SL. Gram-Negative Bacillary Meningitis. Ann Intern Med. ;97:145–147. doi: 10.7326/0003-4819-97-1-145
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Published: Ann Intern Med. 1982;97(1):145-147.
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