CLARENCE J. PETERS, M.D.; KARL M. JOHNSON, M.D.; WILLIAM C. REEVES, M.D.
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To the editor: The paper by Leichtner and co-workers (1) on intensive studies of hepatitis B infection in two families concluded that "horizontal, nonparenteral transmission of hepatitis B, although infrequently recognized, may readily occur in certain American families." Extrapolations from this study may be limited because the index family included four chronic hepatitis B surface antigen (HBsAg) carriers, was composed largely of recent Haitian immigrants, and lived in extremely crowded conditions. Subsequent Annals papers have emphasized homosexual behavior, immunosuppression, parenteral exposure, or contact with clinical specimens in the spread of hepatitis B. Nevertheless, considerable transmission of hepatitis B in the
PETERS CJ, JOHNSON KM, REEVES WC. Hepatitis B in Families. Ann Intern Med. ;97:787. doi: 10.7326/0003-4819-97-5-787_1
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Published: Ann Intern Med. 1982;97(5):787.
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