JORGE J. GONZALEZ, M.D.
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To the editor: We wish to address some of the points raised by Crosby (1) about iron deficiency and pica in the case we reported (2).
After a full diagnostic work-up to exclude continued blood loss, the patient was started on oral therapy that she continued until her readmission with hypokalemia. Despite the gradual improvement in her hematological values, she continued to crave clay. The answer to the question of whether clay ingestion causes or is a symptom of iron deficiency anemia remains controversial. It is difficult to ignore the work of Minnich and associates (3) who showed both in-vitro
GONZALEZ JJ. Iron Deficiency and Pica. Ann Intern Med. 1982;97:789. doi: https://doi.org/10.7326/0003-4819-97-5-789_1
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Published: Ann Intern Med. 1982;97(5):789.
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