RICHARD WILLOUGHBY, M.D.; RICHARD N. GREENBERG, M.D.
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To the editor: Our reading of Part 2 of the June 1982 issue on toxic shock syndrome suggested to us that other organisms may produce pyrogenic exotoxins and occasionally cause toxic shock syndrome. As stated in the accompanying editorial, culture results are available in less than one third of all cases currently reported to the Centers for Disease Control. Although Staphylococcus aureus alone was reported in over 90% of the cases for which there are culture results (1) it may be that other organisms are overlooked and are not reported.
Streptococcal pyrogenic exotoxins have been well described, yet these substances
WILLOUGHBY R, GREENBERG RN. The Toxic Shock Syndrome and Streptococcal Pyrogenic Exotoxins. Ann Intern Med. ;98:559. doi: 10.7326/0003-4819-98-4-559_1
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Published: Ann Intern Med. 1983;98(4):559.
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