ERIC S. JACOBSON, M.D., PH.D; STEPHEN E. STRAUS, M.D.
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To the editor: Wheat and associates (1) have shared a very large experience with histoplasmosis. They found that a sizeable minority of patients (approximately 20%) have cases that will not be identified by current serologic techniques. Such information defines the predictive value of a negative test result and confirms findings reported previously (2), but it is only half of the information needed to evaluate a diagnostic test. To use a diagnostic test intelligently, one must know the predictive value of both negative and positive results (3).
In serologic tests for histoplasmosis, the predictive value of a positive test result has
JACOBSON ES, STRAUS SE. Serologic Tests for Histoplasmosis. Ann Intern Med. ;98:560–561. doi: 10.7326/0003-4819-98-4-560
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Published: Ann Intern Med. 1983;98(4):560-561.
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