MARK R. BURNS, M.D.; DONALD R. SCHOCH, M.D.; ARTHUR I. GRAYZEL, M.D.
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To the editor: Cold urticaria is a well-recognized entity of unknown cause occurring in both familial and acquired forms. We describe a case of cold urticaria in which the inciting agent appears to be an oral contraceptive containing 1 mg of norethindrone and 0.035 mg of mestranol. A MEDLINE search failed to show any cases with such an association.
A 19-year-old Hispanic woman with a benign medical history began taking the medication in October 1981. The next summer she noted the onset of swelling of the face and extremities after swimming. No episodes of dizziness or fainting occurred. During the
BURNS MR, SCHOCH DR, GRAYZEL AI. Cold Urticaria and an Oral Contraceptive. Ann Intern Med. ;98:1025–1026. doi: 10.7326/0003-4819-98-6-1025_3
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Published: Ann Intern Med. 1983;98(6):1025-1026.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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