JOHN M. BOYCE, M.D.; DAVID A. WALSH, PH.D.
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To the editor: Levison and associates (1) described the results of a randomized, prospective study of the efficacy of penicillin versus clindamycin for treatment of anaerobic lung abscess. Results of the trial were analyzed using the Student's t-test or chi-squared test.
The overall results of the study suggest that treatment failures and relapses occur significantly more often with penicillin therapy than with clindamycin. To support their conclusion, the authors state that treatment did not fail in any of the 19 patients treated with clindamycin for at least 10 days, whereas 4 of the 20 patients treated with penicillin for at
BOYCE JM, WALSH DA. Anaerobic Lung Abscess: Clindamycin or Penicillin. Ann Intern Med. ;99:410. doi: 10.7326/0003-4819-99-3-410_1
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Published: Ann Intern Med. 1983;99(3):410.
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