CHARLES WISEMAN, M.D.
This content is PDF only. Please click on the PDF icon to access.
To the editor: The recent report by Poon and associates (1) provides additional evidence associating antigens of mouse mammary tumor virus with human breast cancer. However, a number of questions should be raised regarding details of the methods in their study.
The authors state that their patient, a laboratory worker, had in the past been a negative control but unexpectedly developed a positive reactivity. Nine months later, she developed breast cancer. The authors do not tell us if the patient was resampled, or if the positive specimen was reproducibly reactive, or to what titer was this reactivity identifiable. In normal
WISEMAN C. Breast Cancer and Mouse Mammary Tumor Virus. Ann Intern Med. 1983;99:411. doi: 10.7326/0003-4819-99-3-411_2
Download citation file:
Published: Ann Intern Med. 1983;99(3):411.
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use