IRA M. JACOBSON, M.D.; KURT J. ISSELBACHER, M.D.
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To the editor: Gertz and Kyle (1) have recently shown that functional hyposplenism was found in 24% of their patients with primary systemic amyloidosis. The platelet count was over 300 000/mm3 in 77% of their patients but leukocytosis was not mentioned. In a previous series from the same institution (2) 5% to 10% of such patients had platelet counts greater than 500 000/mm3. The leukocyte count was said to be "normal in most patients." We report a patient with primary amyloidosis and hyposplenism, with marked leukocytosis and thrombocytosis.
A 72-year-old man had a history of fatigue and weight loss for
JACOBSON IM, ISSELBACHER KJ. Amyloidosis and Hyposplenism with Leukocytosis and Thrombocytosis. Ann Intern Med. 1983;99:573. doi: https://doi.org/10.7326/0003-4819-99-4-573_2
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Published: Ann Intern Med. 1983;99(4):573.
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