RICHARD J. ABLIN, PH.D.; MAURICE J. GONDER, M.D.
This content is PDF only. Please click on the PDF icon to access.
To the editor: Recent reports of the development of the acquired immunodeficiency syndrome in hemophiliacs receiving factor VIII and other clotting concentrates have prompted immunologic studies of these patients, such as the one reported by deShazo and colleagues (1). The emergence of the syndrome in hemophiliacs has also prompted us to report some of our observations (2) of the immunosuppressive properties of seminal plasma that might help explain their underlying immunosuppression.
The immunosuppressive factor(s) in seminal plasma is possibly linked to transglutaminase activity. Transglutaminases, as they occur in the blood plasma, are more familiarly known as factors XIII and XIIIa
ABLIN RJ, GONDER MJ. Possibly Immunosuppresive Factors in Blood Products. Ann Intern Med. 1984;100:155–156. doi: https://doi.org/10.7326/0003-4819-100-1-155_2
Download citation file:
Published: Ann Intern Med. 1984;100(1):155-156.
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use